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In a very the latest review, we claimed the identification as well as the characterization of a different atypical opioid receptor with distinctive adverse regulatory Homes toward opioid peptides.1 Our final results confirmed that ACKR3/CXCR7, hitherto called an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is usually a broad-spectr